Exploring Garlic Extract's Role in Endometriosis Treatment

Research Breakthrough in Endometriosis Treatment

A West Australian study will research an alternative pain treatment for endometriosis including using extracts from aged garlic. One in seven women are expected to live with endometriosis, which often causes debilitating pain due to tissue similar to the uterine lining growing outside the uterus.

Study Framework

The Microvascular Modulation in Endometriosis (MMEND) study, conducted at the Curtin Medical Research Institute and Perron Institute, will research whether specific extracts pulled from aged garlic bulbs, as well as certain amino acids, can have an anti-inflammatory effect in patients, thereby minimising pain. Some participants will just receive one of the components while others will receive a combination of both to see which treatment is most effective.

Hopeful Perspectives

Perron Institute and Curtin University head of neurovascular and metabolic diseases John Mamo expressed hope for effective treatment based on evidence pointing to endometriosis being an inflammatory condition, possibly impairing blood flow through capillary vessels. The trial was initiated when Professor Mamo was conducting a different study on migraine pain using a similar treatment, leading to reductions in pain experienced by female participants suffering from endometriosis.

Clinical Coordinator Insights

Clinical trial co-ordinator Emily Redwood, also a dietitian and a Curtin University PhD candidate, stated that if effective, the treatment could be more cost-effective and have fewer side effects than current medications for the condition. “There’s only emerging evidence in this space, so we need more trials like what we’re doing at Curtin and Perron to truly provide health professionals with the evidence needed for recommendations,” she noted.

Participant Recruitment

The study is currently recruiting participants for its 56-week trial, including women with a confirmed diagnosis of endometriosis, living in Perth and aged between 18-45. Exclusions apply for those who are pregnant, breastfeeding, or planning a pregnancy within the next 56 weeks. Interested individuals are encouraged to email mmend@curtin.edu.au.