Innovative Smart Pill Enhances Digestive Diseases Research and Gut Health Monitoring

Sunday, 21 December 2025, 20:01

Smart pill technology is opening new avenues in digestive diseases research and gut health. The swallowable microdevice developed at AIIMS New Delhi collects microbiome samples directly from the intestine. This groundbreaking advancement may significantly improve the diagnosis and treatment of digestive disorders.
Indiatimes
Innovative Smart Pill Enhances Digestive Diseases Research and Gut Health Monitoring

Revolutionizing Digestive Diseases Research

Scientists at IIT Delhi and AIIMS New Delhi have developed a swallowable smart pill that autonomously collects gut microbiome samples from inside the intestine. Funded by the Indian Council of Medical Research (ICMR), this breakthrough addresses critical challenges in studying digestive diseases.

Transformative Technology for Gut Health

  • The pill measures 7 mm by 2.7 mm and is encased in an enteric-coated gelatin shell.
  • It dissolves in the intestine, allowing for site-specific sample collection while preventing contamination.
  • Using nanopore sequencing, researchers identified gut microbes down to the species level, showcasing its potential in monitoring gut health.

Prof. Sarvesh Kumar Srivastava emphasized the importance of exploring the human microbiome, likening it to sending rovers to outer space. This technology holds promise for revolutionizing how disease detection and personalized medicine are approached.

Implications for Future Medical Applications

  1. Direct sampling could lead to early disease detection and improved monitoring of chronic conditions.
  2. Potential for developing targeted treatments based on individual microbiomes.
  3. This research paves the way for subsequent human application studies, ensuring greater relevance in clinical medicine.

The successful testing in Sprague–Dawley rats marks a significant step forward in digestive diseases research and gut health.


This article was prepared using information from open sources in accordance with the principles of Ethical Policy. The editorial team is not responsible for absolute accuracy, as it relies on data from the sources referenced.


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